看见一个 Expert Review of Anticancer Therapy。你们前面用依维莫斯,血、肝肾功能还好。下一步是否考虑索拉非尼+依维莫斯。供你参考。' R& | }- R1 b% {) `
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Currently available feasibility data for possible combination strategies.
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1 s& Z8 h" h2 N& w+ VCombination Feasibility according to preliminary data
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Bevacizumab + sorafenib Yes, reduced dose
. v6 t+ O- k$ V9 F1 WBevacizumab + sunitinib† No
! `1 W6 {$ r# Z$ ^Bevacizumab + temsirolimus Yes
" E3 [/ [% r- p" w9 s" PBevacizumab + everolimus Yes & ]; ]( D7 F$ x z( y- G
Sorafenib + sunitinib ? & D0 y: j% |" n! I* j
Sorafenib + temsirolimus Yes, reduced dose ) D, T0 r4 ?, `
Sorafenib + everolimus Yes, reduced dose
& ?7 r/ M6 r% o6 k$ P9 eSunitinib + temsirolimus† No 6 P* G! `) _; A
Sunitinib + everolimus ? 7 J9 m. y9 s( d
Temsirolimus + everolimus ?
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†Led to US FDA warning.
: U4 \0 h. L7 P! L I?: As yet unattempted combination.: M6 F3 g( i, B% P, p
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